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Anba Pharma AMG-176 CAS No.: Unknown .. Product #: Anba-002959

AMG-176

Catalog No.: Anba-002959
Weight: 0
Call for Price: 610-883-0668

AMG-176 is an inhibitor of induced myeloid leukemia cell differentiation protein MCL-1 (myeloid cell leukemia-1), with potential pro-apoptotic and antineoplastic activities. Upon administration, AMG 176 binds to and inhibits the activity of MCL-1. This disrupts the formation of MCL-1/Bcl-2-like protein 11 (BCL2L11; BIM) complexes and induces apoptosis in tumor cells. MCL-1, an anti-apoptotic protein belonging to the Bcl-2 family of proteins, is upregulated in cancer cells and promotes tumor cell survival.

Chemical
CAS Num Unknown
IUPAC Chemical Name Unknown
Synonym AMG-176; AMG 176; AMG176.
Solubility Soluble in DMSO
Biological
Targets and Effects myeloid leukemia cell differentiation protein
Pathways Apoptosis
Physical
Appearance Solid powder
Purity >98% (or refer to the Certificate of Analysis)
Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shelf Life >2 years if stored properly

Mailing Address

Anba Pharma Company
3-H Gill Street, Suite 300
Woburn, MA 01801
United State

Our Contact Info.

Tel: 1+610-883-0668

Email: sales@AnbaPharma.com

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