Your shopping cart is empty!
Anba Pharma Acyclovir CAS No.: 59277-89-3 .. Product #: Anba-002703 Regular price: $50.00 $50.00


Catalog No.: Anba-002703
Weight: 100mg

Price: $50.00

Available Options

* Weight:
- +

Acyclovir is an antiviral agent with activity against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) and varicella zoster virus. Acyclovir is converted by a herpesvirus enzyme into acyclovir triphosphate that inhibits the synthesis of deoxyribonucleic acid (DNA) molecules in the virally infected cells, thereby inhibiting viral replication. It induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).

1: Srinivas NR. The Interesting Case of Acyclovir Delivered Using Chitosan in Humans: Is it a Drug Issue or Formulation Issue? Pharm Res. 2015 Oct 16. [Epub ahead of print] PubMed PMID: 26474764.
2: Sahu PK, Umme T, Yu J, Nayak A, Kim G, Noh M, Lee JY, Kim DD, Jeong LS. Seleno-acyclovir and -ganciclovir: A Discovery of a New Template for Antiviral Agents. J Med Chem. 2015 Oct 13. [Epub ahead of print] PubMed PMID: 26460883.
3: Kazi M, Al-Amri KA, Alanazi FK. The role of lipid-based drug delivery systems for enhancing solubility of highly selective antiviral agent acyclovir. Pharm Dev Technol. 2015 Oct 13:1-10. [Epub ahead of print] PubMed PMID: 26458371.
4: Sánchez-Sánchez MP, Martín-Illana A, Ruiz-Caro R, Bermejo P, Abad MJ, Carro R, Bedoya LM, Tamayo A, Rubio J, Fernández-Ferreiro A, Otero-Espinar F, Veiga MD. Chitosan and Kappa-Carrageenan Vaginal Acyclovir Formulations for Prevention of Genital Herpes. In Vitro and Ex Vivo Evaluation. Mar Drugs. 2015 Sep 18;13(9):5976-92. doi: 10.3390/md13095976. PubMed PMID: 26393621; PubMed Central PMCID: PMC4584363.
5: Vaithianathan S, Haidar SH, Zhang X, Jiang W, Avon C, Dowling TC, Shao C, Kane M, Hoag SW, Flasar MH, Ting TY, Polli JE. Effect of Common Excipients on the Oral Drug Absorption of Biopharmaceutics Classification System Class 3 Drugs Cimetidine and Acyclovir. J Pharm Sci. 2015 Sep 16. doi: 10.1002/jps.24643. [Epub ahead of print] PubMed PMID: 26375604.
6: Lee HJ, Kim JM, Kim GW, Mun JH, Song M, Kim HS, Kim BS, Kim MB, Ko HC. Fixed drug eruption due to acyclovir, valacyclovir and famciclovir. J Eur Acad Dermatol Venereol. 2015 Sep 15. doi: 10.1111/jdv.13261. [Epub ahead of print] PubMed PMID: 26369523.
7: An J, Li G, An T, Nie X. Indirect photochemical transformations of acyclovir and penciclovir in aquatic environments increase ecological risk. Environ Toxicol Chem. 2015 Sep 10. doi: 10.1002/etc.3238. [Epub ahead of print] PubMed PMID: 26356329.
8: Al-Ghabeish M, Xu X, Krishnaiah YS, Rahman Z, Yang Y, Khan MA. Influence of drug loading and type of ointment base on the in vitro performance of acyclovir ophthalmic ointment. Int J Pharm. 2015 Sep 4;495(2):783-791. doi: 10.1016/j.ijpharm.2015.08.096. [Epub ahead of print] PubMed PMID: 26343911.
9: Kharia AA, Singhai AK. Development and optimisation of mucoadhesive nanoparticles of acyclovir using design of experiments approach. J Microencapsul. 2015 Sep;32(6):521-32. doi: 10.3109/02652048.2015.1010457. Epub 2015 Aug 18. PubMed PMID: 26333938.
10: Zhou C, Chen J, Xie Q, Wei X, Zhang YN, Fu Z. Photolysis of three antiviral drugs acyclovir, zidovudine and lamivudine in surface freshwater and seawater. Chemosphere. 2015 Nov;138:792-7. doi: 10.1016/j.chemosphere.2015.08.033. Epub 2015 Aug 18. PubMed PMID: 26295538.
CAS Num 59277-89-3
Chemical Formula C8H11N5O3
Molecular Weight 225.21
IUPAC Chemical Name 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
Exact Mass 225.08619
Elemental Analysis C, 42.67; H, 4.92; N, 31.10; O, 21.31
Synonym Acyclovir; Acycloguanosine; Aciclovir; Zovirax; Vipral.
Solubility Soluble in DMSO, not in water
Targets and Effects HSV-1 and HSV-2
Pathways Apoptosis
Appearance Solid powder
Purity >98% (or refer to the Certificate of Analysis)
Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shelf Life >2 years if stored properly

Mailing Address

Anba Pharma Company
3-H Gill Street, Suite 300
Woburn, MA 01801
United State

Our Contact Info.

Tel: 1+610-883-0668


Subscribe to our Newsletter

Stay Updated With Our Latest Products.

Please publish modules in offcanvas position.